Pre-implantation Genetic Diagnosis

Pre-implantation genetic diagnosis is a specialised procedure conducted in association with IVF that identifies genetic defects in embryos before they are transferred. It is a high technology that can help couples who know of genetic risks to have a healthy baby. PGD entails the screening of embryos for some genetic conditions that will reduce the chances of inherited disorders and ensure only healthy embryos are transferred.

Dr. Kamaraj preimplantation genetic diagnosis

How Does Pre-implantation Genetic Diagnosis Work?

Pre-implantation diagnosis starts with the IVF procedure, eggs are extracted from the ovaries and put into a specially designed, artificially controlled setting within a lab setting and permitted to fertilise with the sperm. But at a perfect growth stage with an embryo nowadays that would roughly be at 5th or simply referred to as blastocysts stage, cell lines are transferred to a diagnosis for genetic inspection. The removed cells undergo a complete diagnosis to detect genetic abnormalities, such as:

  • Single gene disorders (e.g., cystic fibrosis, thalassemia)
  • Chromosomal abnormalities (e.g., Down syndrome)
  • Sex-linked disorders (e.g., Duchenne muscular dystrophy)

Only the normal embryos are moved into the uterus. It increases the chances of pregnancy and reduces the chances of miscarriage.

What is Pre-implantation Genetic Testing?

Pre-implantation genetic testing refers to the broader term encompassing various techniques for genetic screening performed during IVF. PGT encompasses:

pre implantation genetic diagnosis for embryos
  • Pre-implantation Testing for Aneuploidy (PGT-A) Check for chromosomal disorders to prevent inappropriate numbers of chromosomes.
  • Pre-implantation testing for monogenic disorder (PGT-M) Perseverance of a predisposition risk of single gene disorders.
  • Pre-implantation testing for structural rearrangement (PGT-SR) Chromosomal reorganisation.

3-Step Testing Approach at Dr. Kamaraj Hospital

Dr Kamaraj Hospital (KHPL) provides a structured and efficient 3-step approach to pre-implantation genetic diagnosis:

Consultation and Assessment

At KHPL, our experienced experts evaluate your medical history, fertility health, and genetic risks to determine your eligibility for PGT or PGD.

Embryo Biopsy and Testing

Our expert doctors ensure that biopsies are carefully performed at the blastocyst stage during the IVF cycle, using advanced genetic testing technologies for precise detection of anomalies.

Embryo Transfer

Only those embryos that are free from genetic defects and healthy are transferred. The remaining healthy embryos can be stored frozen for subsequent transfer.

Why Choose Dr. Kamaraj Hospital for Pre-implantation Genetic Diagnosis?

Dr. Kamaraj Hospital is one of the trusted names in reproductive medicine and genetic diagnosis, as the hospital stands out for its comprehensive and patient-focused care. Our advanced laboratory, equipped with the latest technologies, ensures precise genetic testing and analysis. A highly trained team of expert embryologists, genetic counsellors, and fertility specialists collaborate to provide personalised treatment plans tailored to individual genetic and reproductive needs. We walk our patients through the journey, from counselling and testing to implanting, so that service is seamless, with care entailed throughout the process.

Best Sexologist in Chennai Dr. Kamaraj

Need more information?

Take the first step towards a healthy pregnancy and learn more about our pre-implantation genetic diagnosis services.

FAQs

Ideal candidates for PGD are couples with a history of genetic disorders, recurrent miscarriages, or unexplained infertility.

Yes, PGD is a minimally invasive procedure, and studies show it does not adversely affect embryo development or implantation potential.

The time required for the test is typically 1-2 weeks, which depends on the complexity of genetic analysis.

Although PGD can determine the sex of the embryo, its application for non-medical gender selection is banned in many countries, including India.

Meet Our Doctor

Best Sexologist in Chennai Dr. T Kamaraj

Dr. T. Kamaraj

Sexologist & Male Infertility Specialist

MBBS degree and advanced qualifications in obstetrics and gynaecology
Infertility Specialist Dr. J S Jeyarani Kamaraj

Dr. J. S. Jeyarani Kamaraj

Infertility Specialist

MBBS degree and advanced qualifications in obstetrics and genecology, including an MD and a Diploma in Gynecology and Obstetrics (DGO)