Intracytoplasmic Sperm Injection (ICSI)
Intracytoplasmic Sperm Injection (ICSI) is an advanced assisted reproductive technology (ART) that enhances the chances of fertilization during In Vitro Fertilization (IVF). In ICSI, a single, healthy sperm is directly injected into the center of a mature egg using a specialized microscopic needle. This procedure is particularly beneficial for couples facing severe male infertility or other fertilization challenges.
When is ICSI Recommended?
ICSI is a highly effective treatment for couples experiencing:
- Severe Male Factor Infertility:
- Low sperm count (Oligospermia)
- Poor sperm motility (Asthenozoospermia)
- Abnormal sperm shape (Teratozoospermia)
- Absence of sperm in the ejaculate (Azoospermia) due to blockages or testicular issues.
- Previous Failed IVF Cycles: Couples with previous IVF cycles that resulted in failed fertilization benefit from ICSI.
- Unexplained Infertility: In cases where no clear cause for infertility is identified, ICSI improves fertilization chances.
- Use of Surgically Retrieved Sperm:
- Sperm retrieved directly from the testes or epididymis through procedures like TESA (Testicular Sperm Aspiration) or PESA (Percutaneous Epididymal Sperm Aspiration).
- Fertilization with Frozen Eggs or Sperm: ICSI ensures higher success rates when frozen gametes are used.
- Genetic Abnormalities: Couples undergoing Preimplantation Genetic Testing (PGT) may opt for ICSI to maximize fertilization success.
How is ICSI Performed?
ICSI is a highly precise and controlled procedure performed as part of an IVF cycle. The steps include:
- Ovarian Stimulation: Hormonal medications stimulate the ovaries to produce multiple mature eggs. Regular ultrasound monitoring ensures optimal follicle growth.
- Egg Retrieval: Mature eggs are retrieved from the ovaries using a thin needle under ultrasound guidance
- Sperm Collection and Preparation: A semen sample is collected and processed in the laboratory to isolate healthy, motile sperm. In cases of severe male infertility, sperm may be retrieved directly from the testes or epididymis through surgical methods like TESA or PESA.
- Microscopic Injection: A single, high-quality sperm is carefully selected under a high-powered microscope. Using a fine needle, the sperm is injected directly into the center of a mature egg to ensure fertilization.
- Embryo Development and Transfer: Fertilized eggs (embryos) are cultured in the lab for 3-5 days. The best-quality embryo(s) are transferred into the uterus to achieve implantation.
- Pregnancy Test: A pregnancy test is conducted 10-14 days after embryo transfer to confirm success.
Benefits of ICSI
ICSI is one of the most effective fertility treatments for couples facing male infertility and fertilization issues. Key benefits include:
- High Fertilization Success: By directly injecting sperm into the egg, ICSI bypasses natural fertilization challenges.
- Treatment for Severe Male Infertility: ICSI is ideal for low sperm count, poor motility, or abnormal sperm morphology.
- Effective with Surgically Retrieved Sperm: ICSI enables fertilization using sperm retrieved through TESA or PESA.
- Improved IVF Success Rates: For couples with previous failed IVF cycles, ICSI increases the likelihood of successful fertilization.
- Flexibility with Frozen Gametes: ICSI can be performed using frozen sperm or eggs, offering flexibility for fertility preservation.
Symptoms of Male Infertility Addressed by ICSI
ICSI helps address male infertility symptoms, including:
- Low sperm count or poor motility
- Ejaculation problems, such as retrograde ejaculation
- Structural issues like blockages in the reproductive tract
- Hormonal imbalances affecting sperm production
- Unsuccessful fertilization during previous IVF attempts
Complications of Untreated Male Infertility
If left untreated, male infertility can result in:
- Emotional and Mental Stress: Struggling with infertility can cause anxiety, depression, and emotional strain in relationships.
- Increased Fertility Challenges: Delays in treatment may further reduce sperm quality and fertility potential.
- Genetic Concerns: Untreated infertility due to genetic factors may result in transmission to offspring.
Why Choose Dr. Kamaraj Group of Hospitals and IIRM for ICSI?
Advanced Technology: State-of-the-art equipment ensures precise sperm selection and embryo handling.
Tailored Treatment Plans: Personalised fertility solutions are designed based on each couple’s unique needs.
Comprehensive Support: From diagnosis to post-treatment care, we provide emotional and medical support throughout your journey.
Proven Results: Our ICSI success rates have helped numerous couples overcome male infertility and achieve parenthood.
Need more information?
Overcome male infertility with Intracytoplasmic Sperm Injection (ICSI)
FAQ
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Meet Our Doctor
Dr. T. Kamaraj
Sexologist & Male Infertility Specialist
Dr. J. S. Jeyarani Kamaraj
Infertility Specialist